Current treatments for hair loss are limited to two FDA-approved drugs, minoxidil and finasteride, which have mixed results. However, this too has side effects, an interesting one being that it boosts cosmetically unwanted hair growth. This led to the discovery that CsA reduces the expression of SFRP1, a protein that inhibits the development and growth of many tissues, including hair follicles.
The drug called WAY-316606 was meant to treat osteoporosis which leaves people with brittle bones.
The findings were published yesterday in the open access journal PLOS Biology.
There is a third option of a hair transplant, but this can be costly and out of reach for many men.
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If this could be developed into an effective treatment, then it could have a significant impact on those suffering from hair loss, which for many can cause psychological and mental distress.
The researchers began by looking at the drug Cyclosporine A (CsA), which has been used in the treatment of autoimmune diseases for decades and has a number of side effects, one of which is hair growth. Hair growth, however, is the least problematic side-effect of CsA, leading project leader, Nathan Hawkshaw, to look for another solution.
The team of researchers conducted experiments where they applied the substance to human hair follicles donated by hair transplant patients.
But they could soon have the choice between being bald or having a thick thatch of hair, as scientists claim they might have found a cure for male pattern baldness. and people could see results within DAYS.
Have you noticed your hair thinning as you get older?
The study was released on Tuesday and suggests the compound was able to prolong anagen, which is the active growth phase of hair follicles.