Reports say that the students of the Dharampur Government Middle School, which is located along the national highway, were about to cross the National Highway 77 after school.
The heart-rending incident occurred under Minapur police station area, about 10 km from the district headquarters in the afternoon when the school got over and the students were on their way home.
All the injured children were admitted to a hospital in Muzaffarpur.
Beside this, three people were killed and seven injured in separate road accidents in Amethi district, police said today.
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"The injured children have been rushed to Sri Krishna Memorial College and Hospital (SKMCH)".
"So far, nine deaths have been confirmed", a senior police official of Muzaffarpur said.
Almost three weeks ago, 4 people were killed and one critically injured after a passenger train ran over 5 people while they were crossing the railway track in Bihar's Siwan district in the early hours of the morning.
RJD leader Tejashwi Yadav hit out at Bihar CM Kumar and Deputy CM Sushil Kumar Modi over the incident.