"We were 1-0 up and suddenly we lost two goals and we don't know where they came from".
There was a surprise omission from the the Gunners squad as Sanchez was left out amid reports of a move to Manchester United.
Hector Bellerin opened the scoring in the 52nd for Arsenal, which is in sixth place and has dropped five points off the Champions League qualification positions.
"It's a massive lift".
"They were focused and the attitude is one thing, but at that level it is a combination of quality and attitude, and today I question more the quality of what we have created, than the attitude of the players".
"We played with tiredness". We had to win the game.
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The Gunners got off to a positive and hit the upright in the opening 10 minutes through Ainsley Maitland-Niles' powerful strike.
Despite dictating much of the early possession Arsenal clearly missed their more illustrious attacking talents with Alexandre Lacazette cutting a lonely figure without the cutting edge of Sanchez and the injured Mesut Ozil.
The break came at the wrong time for the hosts who found themselves behind soon after when Bellerin - set free by a superb Iwobi ball - fired through Begovic's hand.
First Petr Cech was unable to cut out Fraser's teasing cross with Wilson converting before Ibe smashed home after Wilson did brilliantly to tee him up.
The Gunners defeat means they are still yet to win in 2018, and have only take maximum points from three out of 12 Premier League fixtures this season.
Arsenal will now look to banish the disappointment of defeat at Bournemouth by beating Crystal Palace at the Emirates Stadium next weekend, a game which is followed by an EFL Cup semi-final second leg tie against Chelsea; the first leg ended 0-0 at Stamford Bridge.