Arsenal Confirmed Lineup vs Southampton: Mertesacker in for Mustafi

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All I can do when I get an opportunity is play as well as I can and show the boss what I can do. "They are a top team".

They are a really strong side. But I adjust always what suits the players, the quality of the players, the balance of the team. I felt that even when I was a 16-year-old and I was with players here at Arsenal who were worldwide players, and I believed I was good enough to be in the team.

Shkodran Mustafi has been ruled out for the encounter, and we could potentially see Per Mertesacker feature in central defence alongside Laurent Koscielny and Nacho Monreal.

Santi Cazorla is the only other injury absentee for Arsenal, with Wenger admitting that the midfielder is back at "zero" having required another operation on his problematic ankle. It took them a while to adjust to the pace of the game and they had the power up front and they surprised us a little bit with their pace and after that we played remarkably going forward but, as well, we did not take enough of our chances.

Should Wenger look at changing the system?

Xhaka and Ramsey should start in the central midfield and the likes of Bellerin and Kolasinac must play in the wing-back positions.

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Southampton are still without defender Cedric Soares who is sidelined with a hamstring injury.

Charlie Austin, Shane Long and Manolo Gabbiadini are all in contention to start against the Gunners, with Pellegrino likely to stick to his tactics of deploying a lone striker.

Arsenal finished in fifth place in the Premier League table last term to miss out on a Champions League spot.

Arsenal haven't won successive away league games against Southampton since August 1997.

A 6-0 mauling of BATE Borisov in the Europa League on Thursday will raise spirits heading into a fixture that the Gunners enjoyed success in last season, with back-to-back victories at St Mary's in both the Premier League and FA Cup.

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