Coutinho was left out of Liverpool's squad for the 5-0 Premier League thrashing at Manchester City, agreeing with manager Klopp that he needed to do work to build his fitness after his absence over the opening weeks of the season.
The playmaker has returned to full training at Melwood since participating for Brazil in the recent worldwide break, but was left out of the squad for the 5-0 defeat to Manchester City on the weekend. The Reds will host Sevilla in their UCL opener and even though the game will be played at Anfield Road, it appears to be a complicated fixture for Jürgen Klöpp's men.
In early team news Liverpool can not call on Nathaniel Clyne or Adam Lallana, while Danny Ings and Philippe Coutinho are minor doubts.
Sevilla have scored five times in three Liga matches this season, and they will face a defence that conceded five times against Manchester City a few days ago.
Coutinho is not a direct replacement for Mane as he plays in a more central position, but Klopp may look to introduce him in tomorrow night's Champions League game against Sevilla, even if he is used from the bench to start with. "I'm happy to be at the club with these players", Salah recently told Liverpool website.
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All those opponents are beatable and they should have additional motivation to win this first game against Sevilla at Anfield.
It happened in the 2015-16 UEFA Europa League, and Sevilla won 3-1. They missed out on a trophy as well as automatic Champions League qualification.
"I know when the draw was made people were saying we are lucky with the group, but then you watch Sevilla and analyse them and think: 'Oh my God, that's real football, '" he added. Liverpool however ended up insisting that they will not sell the player and went on to reject numerous offers from the Catalan giants. "We have a lot of experience, we are not rookies and see if we get a good result against a great team".
If Henderson is able to become the game's main midfield protagonist, Liverpool's chances of success will be significantly enhanced.