"Now we can develop parts of the country we were never able to develop before", Santos said.
At a ceremony in Fonseca, a town in the northern province of Guajira, Santos on Tuesday said the shipment marked "the last breath of the conflict" between the rebels and government forces, which lasted 53 years, Xinhua news agency reported.
"Today effectively marks the final sigh of this conflict, with this disarmament process, with these last containers".
At his side, Mr. Santos has locked up the last container has left, under United Nations supervision, the area of Pondores, one of the 26 where the Farc are grouped together for eight months.
Officials said FARC's weapons will be smelted into peace monuments that will be displayed in Bogota, New York City and Havana, Cuba.
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"Our mission has, up to today, gathered 8,112 arms in these containers and destroyed nearly 1.3 million cartridges", United Nations mission chief for Colombia Jean Arnault said at an event to mark the shipment.
The armed struggle, the Farc are now spending in the political struggle, as foreseen by the peace agreement aimed at putting an end to a fratricidal conflict of more than half a century, over the decades, has involved other guerrillas and paramilitaries, making up approximately 7.5 million victims, among the dead, missing and displaced.
From today, the 26 zones of transition across Colombia where the guerrillas have been living since they abandoned their traditional camps are now to be known as zones of reincorporation and training.
Pablo Catatumbo, another FARC leader, said that 1,200 FARC representatives will participate in their constitutive congress, where they will make decisions with regard to their political leadership, party policies, as well as their party's principal objectives.
Seven Farc members have been killed since the beginning of the disarmament in January, according to the foundation for Peace and Reconciliation following the peace process. The FARC has also announced plans to seek a 2018 election alliance with the Colombian Communist Party.