Leicester are winless against the North London club in their past 21 league meetings stretching back to November 1994 and Arsenal's run of 10 straight home victories over Craig Shakespeare's side is the longest for an English top-flight club at home.
The Arsenal boss has been willing to take the risk of Sanchez running down his current contract and leaving the Emirates on a free transfer next summer.
Rumours persist that Sanchez will leave before the window closes, with Wenger suggesting he will also miss the trip to Stoke next weekend.
"Yes", Wenger said in July, as quoted by The Daily Telegraph.
"He had a little abdominal strain that he caught on Sunday morning in training".
Wenger has revealed how uncertainty over his future last season created a "lack of clarity in the dressing room" and saw players asking him what was going on. He had a scan two days ago and he's out for a while.
Himachal Pradesh: Seven people killed after landslide hits Mandi
The army along with the local authorities and the National Disaster Response Force are carrying out a search and rescue operation. One of the buses was on its way to Chamba from Manali, while the other one was on its way to Katra in Jammu from Manali.
Sanchez returned late to pre-season training with the Gunners due to his commitments at the Confederations Cup with Chile and will now have his start to the new Premier League campaign delayed. I don't know - two weeks, one more week.
"He will not play at Stoke".
"We haven't been able to beat them yet but there's always a first time and it would be nice to think it would be Friday night". 'I have sympathy for him.
But the summer has been a good one so far for Arsenal as they have managed to keep some of their key players like Alexis Sanchez, Hector Bellerin and Mesut Ozil, even though the Chilean is still heavily linked with a move away.
While keeping Sanchez to the final year of his contract in a manner is commendable, and you can understand what Wenger's thinking is, what the Arsenal manager needs to weigh is if that decision ends up helping the club or not. I just think we are not open - what I said to you many times - to any offers, anyway.
It's little wonder some of Europe's elite might look to poach the Chile global after Arsenal finished fifth in the Premier League last season.