Such an effort provoked scenes of sheer jubilation at the Emirates Stadium and came just two minutes after fellow substitute Aaron Ramsey looked to have rescued a point for the inconsistent Gunners after blasting in from close range.
Instead, Wenger avoided a third consecutive season-opening loss at the start of his new two-year contract. However, Arsenal and Liverpool could well have something to say about that, especially if the Wembley factor derails Spurs.
Winning the FA Cup in May silenced some of Wenger's most vocal critics, but the triumph still failed to win over all naysayers.
"If you cut the team in half, attacking wise they look great on paper and they showed that with some intricate passing - it was outstanding at times".
It's well known that Arsenal want (and need) to move some players on, but even with that many individuals sidelined, Wenger can still call upon Rob Holding, Calum Chambers, Nacho Monreal and new signing Sead Kolasinac to make up his back three.
Brexit deal not 'back door' to staying in EU: Ministers
A source close to Mr Davis said the papers would highlight the British teams were "on the front foot" in the negotiations. The first will be a proposal for new customs arrangements.
"What matters now is that we win and start in a strong way, which we did not do last season".
When asked what the victory over Antonio Conte's side means for the Gunners, Wenger said: 'It will increase the belief but then you face a shock when the league starts.
The way they ruthlessly pounced on Arsenal mistakes was highlighted by their second via a Albrighton cross for Vardy to tap home at the back post. Vardy knows how to score against Arsenal. It's no doubt going to spoil all of us because the rest of the games are going to suck by comparison.
It has been just over three months since Antonio Conte completed Chelsea's turnaround from finishing 10th in the 2015/16 campaign to be crowned champions in the 2016/17 season and now Premier League is back again for its 25th edition. The first was a kick off.
"Seven goals, fantastic comebacks", the 35-year-old Czech said on his website. During most of the game, the team's defence left much to be desired - that Vardy managed get past six defenders to score his second goal is testament to that.
Arsenal fans had little time to celebrate.